Science Inventory

IRIS Assessment Plan for Ammonia and Ammonium Salts Noncancer Oral (Scoping and Problem Formulation Materials, Suspended)

Notice:

[UPDATE] EPA suspended the Ammonia and Ammonium Salts (noncancer oral exposure) assessment in fiscal year 2019. This assessment may be restarted as Agency priorities change. For more information, visit the IRIS Program Outlook (Apr 2019).

Citation:

U.S. EPA. IRIS Assessment Plan for Ammonia and Ammonium Salts Noncancer Oral (Scoping and Problem Formulation Materials, Suspended). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-18/041, 2018.

Impact/Purpose:

The IAP communicates to the public the plan for assessing each individual chemical and includes summary information on the IRIS Program’s scoping and initial problem formulation, objectives and specific aims for the assessment, and a PECO framework that outlines the evidence considered most pertinent to the assessment; and identification of key areas of scientific complexity.

Description:

In April 2018, EPA released the draft IRIS Assessment Plan for Ammonia and Ammonium Salts Noncancer Oral. An IRIS Assessment Plan (IAP) communicates to the public the plan for assessing each individual chemical and includes summary information on the IRIS Program’s scoping and initial problem formulation; objectives and specific aims for the assessment; the PECO (Populations, Exposures, Comparators, and Outcomes) criteria that outlines the evidence considered most pertinent to the assessment; and identification of key areas of scientific complexity. The PECO provides the framework for developing literature search strategies and inclusion/exclusion criteria, particularly with respect to evidence stream (i.e., human, animal, mechanistic), exposure measures and outcome measures.

Record Details:

Record Type:DOCUMENT( ASSESSMENT DOCUMENT)
Product Published Date:04/16/2018
Record Last Revised:12/14/2020
OMB Category:Other
Record ID: 340338