Citation:

Conley, J., N. Evans, M. Cardon, E. MedlockKakaley, P. Hartig, E. Gray, AND V. Wilson. New(ish) tools in the toolbox: Using in vitro bioassays for cumulative assessment of steroid hormone receptor active compounds in environmental samples. Society of Environmental Toxicology and Chemistry 38th Annual Meeting, Minneapolis, Minnesota, November 12 - 16, 2017.

Impact/Purpose:

This is an abstract for submitted for consideration in the 2017 SETAC Annual Meeting. I was invited to submit an abstract for a session titled "Approaches for deciphering multiple stressors in aquatic environments". As such, the present abstract describes the current state-of-the-science regarding our research group's usage of in vitro bioassays for assessing steroid hormone receptor agonism/antagonism to inform water quality monitoring.

Description:

In vitro assays are currently a high priority tool within USEPA for screening chemicals and samples for biological activity. The work included in this abstract describes the usage and expertise in our research group for using in vitro assays to screen environmental samples for steroid hormone receptor activity in order to complement analytical chemical analyses for assessing water quality and contamination. There is a large amount of interest in the US and internationally in incorporating these assays into water quality monitoring frameworks.

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