Citation:

MedlockKakaley, E., M. Cardon, E. Gray, P. Hartig, AND V. Wilson. Validation of a Glucocorticoid Receptor Effects-Based Environmental Sample Screening Tool. CiT Seminar, Chapel HIll, NC, September 25, 2017.

Impact/Purpose:

Glucocorticoid receptor pharmaceuticals are endocrine active compounds in both humans and wildlife. These compounds have been detected in waste and surface waters domestically and around the world using both analytical chemistry and cell-based bioassay methods. Using an established cell-based assay, many glucocorticoid-specific pharmaceuticals were evaluated, individually and in mixtures. This evaluation of GR-specific pharmaceuticals will enable the differentiation of GR ligands in environmental mixtures samples in future studies. Findings from this study will be presented to peers at UNC-CH for the Cirriculum in Toxicology Seminar Series.

Description:

Abstract describing study and results that will be presented in a seminar presentation to members of UNC-Chapel Hill Curriculum in Toxicology. This seminar presentation will be fulfilling the requirements of the USEPA-UNC Toxicology Cooperative Postdoctoral Training program.

Record Details: