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IRIS Assessment Plan for Nitrate and Nitrite (Scoping and Problem Formulation Materials)
EPA released of the draft IRIS Assessment Plan for Nitrate and Nitrite for public review and comment. This document was discussed at an EPA Science Advisory Board (SAB) Chemical Assessment Advisory Committee (CAAC) meeting on September 27-28, 2017. Information regarding the meeting can be found on the SAB website.
U.S. EPA. IRIS Assessment Plan for Nitrate and Nitrite (Scoping and Problem Formulation Materials). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-17/331, 2017.
This outcome from the release of this document of the draft assessment plan for nitrate and nitrite that will be the subject of an SAB/Chemical Assessment Advisory Committee meeting that will was held September 2017 in order to define the scope and approach for the development of the IRIS assessment for nitrate and nitrite.
In September 2017, EPA released the draft IRIS Assessment Plan (IAP) for Nitrate and Nitrite for public review and comment. This document was discussed at an EPA Science Advisory Board (SAB) Chemical Assessment Advisory Committee (CAAC) meeting on September 27-28, 2017. An IRIS Assessment Plan (IAP) communicates to the public the plan for assessing each individual chemical and includes summary information on the IRIS Program’s scoping and initial problem formulation; objectives and specific aims for the assessment; the PECO (Populations, Exposures, Comparators, and Outcomes) criteria that outlines the evidence considered most pertinent to the assessment; and identification of key areas of scientific complexity. The PECO provides the framework for developing literature search strategies and inclusion/exclusion criteria, particularly with respect to evidence stream (i.e., human, animal, mechanistic), exposure measures and outcome measures.
URLs/Downloads:SAB Activity Page on the Briefing by NCEA on development of IRIS draft assessments
IRIS Assessment Plan for Nitrate and Nitrite (Sep 2017) (PDF,19 pp, 404 KB, about PDF)
Memorandum: SAB Chemical Assessment Advisory Committee Briefing on the Integrated Risk Information System (IRIS) Evolution of Assessment Practices (PDF,4 pp, 181 KB, about PDF)
FR Notice: Sep 18, 2017 Exit
Record Details:Record Type: DOCUMENT (IRIS ASSESSMENT)
Organization:U.S. ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF RESEARCH AND DEVELOPMENT
NATIONAL CENTER FOR ENVIRONMENTAL ASSESSMENT
PROGRAM SUPPORT STAFF