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Environmental and Metabolic Transformations of the Piscicide Antimycin A
Citation:
Kenneke, J. AND T. Sack. Environmental and Metabolic Transformations of the Piscicide Antimycin A. SETAC Europe 26th Annual Meeting, Nantes, FRANCE, May 22 - 26, 2016.
Impact/Purpose:
Presented at SETAC Europe 26th Annual Meeting, Nantes, France, from 22-26 May 2016.
Description:
Antimycin A is a natural occurring product of bacterial fermentation and is an extremely potent inhibitor of mitochondrial respiration. It is toxic to all organisms that depend on mitochondrial respiration; however, there is a large divergence in toxicity, even between closely related species. Fish are extremely sensitive to antimycin A, which has led to the extensive use of antimycin A as a piscicide to eradicate non-native fish species prior to the re-introduction of native species and in aquaculture (e.g., catfish) for the selective removal of scaled fish from ponds prior to restocking. In spite of the long-term use of antimycin A, little information exists on its environmental fate and metabolism.