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METABOLIC ACTIVATION OF 3-(2-CHLOROETHOXY)-1,2-DICHLOROPROPENE: A MUTAGEN STRUCTURALLY RELATED TO DIALLATE, TRIALLATE, AND SULFALLATE
Citation:
Distlerath, L., J. Loper, AND M. Tabor. METABOLIC ACTIVATION OF 3-(2-CHLOROETHOXY)-1,2-DICHLOROPROPENE: A MUTAGEN STRUCTURALLY RELATED TO DIALLATE, TRIALLATE, AND SULFALLATE. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-85/138 (NTIS PB85249837), 1985.
Description:
3-(2-Chloroethoxy)-1,2-dichloropropene (CP), a Samonella promutagen which was recently isolated from a sample of residue organics previously concentrated from drinking water, is structurally related to three other chlorinated promutagens, the S-chloroallyl thiocarbamate herbicides diallate, triallate and sulfollate. These four chloroallyl ether compounds were found to be similar with respect to strain specificity, potency and requirement for specific metabolic activation. (Copyright (c) 1985 Alan R. Liss, Inc.)