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Effect of chlorination on the protein phosphatase inhibition activity for several microcystins
Citation:
Mash, H. AND A. Wittkorn. Effect of chlorination on the protein phosphatase inhibition activity for several microcystins. WATER RESEARCH. Elsevier Science Ltd, New York, NY, 95:230-239, (2016).
Impact/Purpose:
Determined the toxicity of algaltoxins and their chlorination by-products.
Description:
Microcystins are of particular concern due to their toxicity to both humans and animals and are likely the most prominent cyanotoxin observed in freshwater. Although a number of studies have investigated the fate of microcystins and other algal toxins through drinking water treatment facilities, measurement of their potential for toxic activity after chlorination has not been investigated. In this study, six MYC variants are subjected to chlorine oxidation at several pHs. The removal of six MYC variants is measured over time. Simultaneously, the measured protein phosphatase inhibition response of the resulting reaction mixture is measured.
URLs/Downloads:
http://dx.doi.org/10.1016/j.watres.2016.03.024Effect Chlor Protein Phosphatase Inhibition Activity (PDF, NA pp, 3028 KB, about PDF)