EPA Science Inventory

History of Arsenic as a Poison and Medicinal

Citation:

Hughes, M. History of Arsenic as a Poison and Medicinal. Chapter 1, Arsenic: Exposure Source, Health Risks and Mechanisms of Toxicity. John Wiley & Sons, Inc, Hoboken, NJ, 1:4-33, (2015).

Description:

Since ancient times, human exposure to the metalloid arsenic has been both intentional and unintentional. The intentional exposure to arsenic has been to inflict harm on others as well as to be a curative agent for those who are ill. The unintentional exposure has either been from the environment (e.g., drinking water) or from consumer products that either contained arsenic as a known constituent (e.g., wallpaper) or precursors used to make the product were unknowingly contaminated with arsenic (e.g., brewery sugar). Efforts are underway by public health officials in many countries to minimize unintentional environmental exposure. However, arsenic exposure will continue because of its pervasive nature in the environment, its use in commercial products (e.g., semiconductors), the malicious intent of some individuals to commit homicide, and its use as a medicinal agent.

Purpose/Objective:

This book chapter describes the history of arsenic as an intentional and unintentional poison as well as its use as a medicinal agent.

URLs/Downloads:

ORD-004545ABSTRACT.PDF   (PDF,NA pp, 170.831 KB,  about PDF)

Record Details:

Record Type: DOCUMENT (BOOK CHAPTER)
Completion Date: 11/01/2015
Record Last Revised: 09/28/2015
Record Created: 09/28/2015
Record Released: 09/28/2015
OMB Category: Other
Record ID: 309482

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LAB

INTEGRATED SYSTEMS TOXICOLOGY DIVISION

PHARMACOKINETICS BRANCH