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INACTIVATION OF HEPATITIS A VIRUS AND MODEL VIRUSES IN WATER BY FREE CHLORINE AND MONOCHLORAMINE
Citation:
Sobsey, M., T. Fuji, AND P. Shields. INACTIVATION OF HEPATITIS A VIRUS AND MODEL VIRUSES IN WATER BY FREE CHLORINE AND MONOCHLORAMINE. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/D-88/042.
Description:
The kinetics and extent of inactivation of hepatitis A virus (HAV) as well as three other viruses, coxsackievirus B5 (CB5) and coliphages MS2 and X174, by 0.5 mg/l free chlorine, pH 6-10, and 10 mg/1 monochloramine, pH8, in 0.01 M phosphate buffer were determined. These results indicate that HAV is inactivated relatively rapidly by free chlorine but relatively slowly by monochloramine. Coliphage MS2 is a reasonable model to predict reactivation of HAV by free chlorine and inactivation of HAV and CB5 by monochloramine. It is poor model for predicting free chlorine inactivation of CB5 and perhaps some other human enteric viruses.