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Characterization Of Risks Posed By Combustor Emissions
Citation:
Rice, G., J. Swartout, E. Brady-Roberts, D. Reisman, K. Mahaffey, AND B. Lyon. Characterization Of Risks Posed By Combustor Emissions. DRUG AND CHEMICAL TOXICOLOGY. Marcel Dekker Incorporated, New York, NY, 22(1):221-240, (1999).
Impact/Purpose:
journal article
Description:
Risk characterization is the final step of the risk assessment process as practiced in the U.S. EPA. In risk characterization, the major scientific evidence and "bottom-line" results from the other components of the risk assessment process, hazard identification, dose-response assessment, and exposure assessment, are evaluated and integrated into an overall conclusion about the risks posed by a given situation. Risk characterization is also an iterative process; the results of a specific step may require re-evaluation or additional information to finalize the risk assessment process. Risks posed by atmospheric emissions are an example of an involuntary human health risk which typically receives a great deal of public attention. Characterization of the risks posed by atmospheric emissions typically requires the use of mathematical models to evaluate: 1) the environmental fate of emitted pollutants, 2) exposures to these pollutants, and 3) human dose-response. Integration of these models results in quantitative risk estimates. The confidence in a quantitative risk estimate is examined by evaluating uncertainty and variability within individual risk assessment components. Variability arises from the true heterogeneity in characteristics within a population or an event; on the other hand, uncertainty represents lack of knowledge about the true value used in a risk estimate. U.S.EPA's 1997 Mercury Study will illustrate some aspects of the risk characterization process as well as the uncertainty and variabilty encourntered in the risk assessment process.