Science Inventory

You are here:

EPA Home » Science Inventory » Microwave assisted alkylation of amines with alcohols; magnetically recoverable catalysis

Microwave assisted alkylation of amines with alcohols; magnetically recoverable catalysis

Contact

http://cfpub.epa.gov/si/si_public_comments.cfm

Citation:

Takkellapati, S. AND M. Nadagouda. Microwave assisted alkylation of amines with alcohols; magnetically recoverable catalysis. Current Organic Chemistry. Bentham Science Publishers, Ltd., Oak Park, IL, 17(20):2332-2337, (2013).

Impact/Purpose:

A greener method for the alkylation of amines with alcohols using magnetic manganese oxide and microwave in the absence of any solvent is developed. This might be very useful for various alkylation reactions of amines. It is estimated that approximately 65% alkylations carried out in pharmaceutical industry are N-alkylation reactions.

Description:

A simple, solvent free microwave assisted alkylation of amines with alcohols catalyzed by manganese oxide impregnated -Fe2O3 is reported.

Record Details:

Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)
Product Published Date:10/01/2013
Record Last Revised:05/30/2014
OMB Category:Other
Record ID: 276383