Impact/Purpose:

We hypothesize that the desirable physicochemical properties that create unique NM functionality can also influence inherent hazards and potential exposure routes. LCnano’s overarching goal is to elucidate NM property-exposure and property-hazard relationships from a life cycle perspective and to provide predictive models for unintended implications of NMs that will improve design of safe nano-enabled products and processes. To inform risk managers, LCnano will employ high throughput functional assays to quantify material attributes that serve as proxies for short- and long-term risk (material exposure, hazard, reactivity, and distribution). To inform designers of nano-enabled products about balances between performance and risk, LCnano will evaluate nano-enabled products for facilitating direct and translational methods in the development of material property-exposure and property-hazard relationships for identifying and subsequently minimizing risk for a wide array of existing products, helping ensure sustainable design of future, transformative nano-enabled products.

Description:

Because engineered nanomaterials (NMs) have transformative benefits to individuals and society, they are being incorporated into many products. However, tremendous uncertainty presently exists in our ability to predict or manage risks from nano-enabled products across their life cycles. This project involves an interdisciplinary team of chemists, toxicologists, scientists, engineers, and social scientists to evaluate the trade-offs between intended function of NMs in products and risks to humans and the environment across their life cycle from creation, through use and disposal.

Record Details:

Record Type:PROJECT( ABSTRACT )

Start Date:03/19/2014

Completion Date:03/18/2018

Record ID: 273128

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Project Information:

Approach :

LCnano will systematically evaluate four product lines expected to have variable NM release rates (i.e., dispersed in liquids used in industrial manufacturing (e.g., polishing agents), dispersed in products (e.g., foods), embedded in composite polymers (e.g., thermoplastics, membranes for water filtration), and coated on the surfaces of flexible polymeric materials (e.g., textiles) using four high-volume NMs (titanium dioxide, silicon dioxide, nano-silver, and multi-wall carbon nanotubes) that exhibit properties unique from each other and properties similar to other emerging NMs. Experiments conducted using model and commercial nano-enabled products will evaluate yield and byproducts during NM synthesis and examine release rates and characteristics using novel nanometrology.

Cost :$5,000,000.00

Research Component :Endocrine Disruptors