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IRIS Toxicological Review of Tert-Butyl Alcohol (TBA) (Public Comment Draft, 2016)
EPA announced the release of the IRIS Toxicological Review of tert-Butyl Alcohol (tert-Butanol or tBA) (Public Comment Draft) for a 60-day public comment and review period. tBA was one of the chemicals discussed at the June 29-30, 2016 IRIS Public Science Meeting.
Citation:
U.S. EPA. IRIS Toxicological Review of Tert-Butyl Alcohol (TBA) (Public Comment Draft, 2016). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-16/079, 2016.
Impact/Purpose:
This draft report is being released for public viewing and comment prior to a public meeting, providing an opportunity for the IRIS Program to engage in early discussions with stakeholders and the public on data that may be used to identify adverse health effects and characterize exposure-response relationships. EPA welcomes all comments on the draft literature search, preliminary evidence tables, and preliminary exposure-response arrays, such as remarks on the following: • the clarity and transparency of the materials; • the approach for identifying pertinent studies; • the selection of studies for data extraction to preliminary evidence tables and exposure-response arrays; • any methodological considerations that could affect the interpretation of or confidence in study results; and • any additional studies published or nearing publication that may provide data for the evaluation of human health hazard or dose-response relationships.
Description:
EPA is developing an Integrated Risk Information System (IRIS) assessment of tert-butyl Alcohol (tert-butanol or tBA) and has released the public comment draft assessment for public comment and external peer review. When final, the assessment will appear on the IRIS database.
URLs/Downloads:
Toxicological Review of tert-Butyl Alcohol (Public Comment Draft) (PDF, 140 pp, 3050 KB, about PDF)Toxicological Review of tert-Butyl Alcohol - Supplementary Information (Public Comment Draft) (PDF, 107 pp, 2096 KB, about PDF)
Draft Charge to the Science Advisory Board for the IRIS Toxicological Review of tert-Butyl Alcohol (PDF, 5 pp, 172 KB, about PDF)
ETBE kidney tables for the draft IRIS Assessment of tert-Butyl Alcohol (PDF, 18 pp, 1069 KB, about PDF)
FR Notice: May 16, 2016
IRIS Public Science Meeting (Dec 2013)
IRIS Public Science Meeting (Jun 2016)