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Bacillus thuringiensis as a surrogate for Bacillus anthracis in aerosol research
Tufts, J., W. Calfee, S. Lee, AND S. Ryan. Bacillus thuringiensis as a surrogate for Bacillus anthracis in aerosol research. WORLD JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY. Springer, New York, NY, 30(5):1453-1461, (2014).
Characterization of candidate surrogate spores prior to experimental use is critical to confirm that the surrogate characteristics are as closely similar as possible to those of the pathogenic agent of interest. This review compares the physical properties inherent to spores of Bacillus anthracis (Ba) and Bacillus thuringiensis (Bt) that impact their movement in air and interaction with surfaces, including size, shape, density, surface morphology, structure and hydrophobicity. Also evaluated was the impact of irradiation on the physical properties of both Bacillus species.
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BACILLUS THURINGIENSIS AS A SURROGATE FOR BACILLUS ANTHRACIS IN AEROSOL RESEARCH Exit
Record Details:Record Type: DOCUMENT (JOURNAL/PEER REVIEWED JOURNAL)
Organization:U.S. ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF RESEARCH AND DEVELOPMENT
NATIONAL HOMELAND SECURITY RESEARCH CENTER
DECON AND CONSEQUENCE MANAGEMENT DIVISION