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Web-based Interspecies Correlation Estimation (Web-ICE) for Acute Toxicity: User Manual 3.2
Citation:
Raimondo, Sandy, CrystalR Jackson, AND M. Barron. Web-based Interspecies Correlation Estimation (Web-ICE) for Acute Toxicity: User Manual 3.2. U.S. EPA Office of Research and Development, Washington, DC, EPA/600/R-12/603, 2013.
Impact/Purpose:
Provide user guidance and instruction for Web-ICE v. 3.2.1
Description:
The Web-ICE Endangered Species module simultaneously estimates toxicity to taxa representing threatened or endangered species using up to 25 surrogates. This module batch processes toxicity values for endangered species from all species, genus, and family level models available for the selected endangered species and entered surrogates. The list of threatened and endangered species was obtained from the US Fish and Wildlife Service Threatened and Endangered Species module of Environmental Conservation Online System (http://ecos.fws.gov/tess_public; Accessed August 2007), which was linked to Web-ICE species, genus, and family model databases for aquatic organisms (not currently available for algae) and wildlife. Users may predict to all available endangered species within a broad taxonomic groups (e.g., Fishes) or a particular species (e.g., Atlantic Salmon, Salmo salar). This manual provides step-by-step instructions for using Web-ICE, as well as information on the expanded databases, model development, model validation, and user guidance on model selection and interpretation. User guidelines outlined in the Guidance for Model Selection and Use section of this manual are recommended to ensure high confidence and low uncertainty in model predictions used in risk assessment.