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IRIS Toxicological Review of 1,4-Dioxane (With Inhalation Update) (Final Report)
Citation:
U.S. EPA. IRIS Toxicological Review of 1,4-Dioxane (With Inhalation Update) (Final Report). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-11/003F, 2013.
Impact/Purpose:
1,4-Dioxane is commonly used as a solvent, cleaning agent, chemical stabilizer, surface coating, adhesive agent, and an ingredient in chemical manufacture.
Description:
The final IRIS Toxicological Review of 1,4-dioxane (with inhalation update) provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to 1,4-dioxane. Human health risk concerns for 1,4-dioxane are primarily related to exposure from drinking, ground, and surface waters, although these exposure concerns have not been well characterized. 1,4-Dioxane is commonly used as a solvent, cleaning agent, chemical stabilizer, surface coatings, adhesive agent, and an ingredient in chemical manufacture.