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IRIS Toxicological Review of Ammonia (Interagency Science Consultation Draft)
Citation:
U.S. EPA. IRIS Toxicological Review of Ammonia (Interagency Science Consultation Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-11/013C, 2012.
Impact/Purpose:
EPA is undertaking an Integrated Risk Information System (IRIS) health assessment for ammonia. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information in support of two steps of the risk assessment paradigm, i.e., hazard identification and dose-response evaluation. IRIS assessments are used in combination with specific situational exposure assessment information to evaluate potential public health risk associated with environmental contaminants.
Description:
On June 1, 2012, the draft Toxicological Review of Ammonia and the draft charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science consultation materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Ammonia and the charge to external peer reviewers, are posted on this site.
URLs/Downloads:
IRIS Toxicological Review of Ammonia (Interagency Science Consultation Draft) Oct 2011 (PDF, 151 pp, 1243 KB, about PDF)Draft Charge to External Peer Reviewers (Interagency Science Consultation Draft) Oct 2011 (PDF, 2 pp, 30 KB, about PDF)
IRIS Toxicological Review of Ammonia (2nd Interagency Science Consultation Draft) Feb 2012 (PDF, 94 pp, 911 KB, about PDF)
IRIS Toxicological Review of Ammonia, Supplemental Information (2nd Interagency Science Consultation Draft) Feb 2012 (PDF, 65 pp, 701 KB, about PDF)
Draft Charge to External Peer Reviewers (2nd Interagency Science Consultation Draft) Feb 2012 (PDF, 2 pp, 32 KB, about PDF)
EPA's Response and Comments from the Interagency Science Consultation (PDF, 4 pp, 56 KB, about PDF)
1. CDC ATSDR Ammonia IASC Comments - Nov 2011 (PDF, 2 pp, 29 KB, about PDF)
2. CDC ATSDR Ammonia IASC Comments - Feb 2012 (PDF, 1 pp, 27 KB, about PDF)
3. CEQ Ammonia IASC Comments - Mar 2012 (PDF, 1 pp, 49 KB, about PDF)
4. USDA Ammonia IASC Comments - Nov 2011 (PDF, 1 pp, 40 KB, about PDF)
5. Consolidated Comments from IRIS Interagency Reviewers on the Format and Preamble in the Science Consultation Draft Ammonia Assessment (PDF, 7 pp, 178 KB, about PDF)