EPA Science Inventory

IRIS Toxicological Review of Diisononyl Phthalate (Dinp) (Preliminary Assessment Materials)

Notice:

EPA hosted an IRIS public science meeting on October 29-30, 2014, to provide an opportunity for the public to give input and participate in an open discussion regarding preliminary materials that were prepared for the IRIS chemicals, hexavalent chromium (Cr(VI)) and diisononyl phthalate (DINP), prior to the development of the draft assessment.

Citation:

U.S. EPA. IRIS Toxicological Review of Diisononyl Phthalate (Dinp) (Preliminary Assessment Materials). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-14/242, 2014.

Description:

In August 2014, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for DINP to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in comments on the following:

  • Draft literature search strategies
    • The approach for identifying studies
    • The screening process for selecting pertinent studies
    • The resulting list of pertinent studies
  • Preliminary evidence tables
    • The process for selecting studies to include in evidence tables
    • The quality of the studies in the evidence tables
The literature search strategy, which describes the processes for identifying scientific literature, contains the studies that EPA considered and selected to include in the evidence tables. The preliminary evidence tables and exposure-response arrays present the key study data in a standardized format. The evidence tables summarize the available critical scientific literature. The exposure-response figures provide a graphical representation of the responses at different levels of exposure for each study in the evidence table.

Purpose/Objective:

N/A

URLs/Downloads:

Literature selection process for the DINP primary literature (dynamic literature link - generated by HERO, leaving the IRIS website)

Primary literature search references sorted by author (DINP)

Scoping information, preliminary literature search, associated strategy and evidence tables for DINP   (PDF,131 pp, 1811 KB,  about PDF)

IRIS October 2014 Meeting & Presentations

Literature selection process for the DINP targeted epidemiological literature (dynamic literature link - generated by HERO)

Targeted literature search for epidemiological references sorted by author (DINP) (dynamic literature link - generated by HERO)

Record Details:

Record Type: DOCUMENT (IRIS ASSESSMENT)
Start Date: 08/09/2014
Projected Completion Date: 11/25/2013
Record Last Revised: 12/06/2016
Record Created: 08/09/2011
Record Released: 08/09/2014
OMB Category: Other
Record ID: 237476

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR ENVIRONMENTAL ASSESSMENT

IMMEDIATE OFFICE