IRIS Toxicological Review of Tert-Butyl Alcohol (TBA) (Preliminary Assessment Materials, 2013)
EPA hosted an IRIS public science meeting on December 12-13, 2013, to provide an opportunity for the public to give input and participate in an open discussion regarding preliminary materials that were prepared for the IRIS chemical, tert-Butyl Alcohol (tBA), prior to the development of the draft assessment.
Citation:
U.S. EPA. IRIS Toxicological Review of Tert-Butyl Alcohol (TBA) (Preliminary Assessment Materials, 2013). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-13/107, 2013.
Impact/Purpose:
EPA is undertaking a new health assessment for t-butyl alcohol (TBA) for the Integrated Risk Information System (IRIS). The outcome of this project will be a Toxicological Review and IRIS and IRIS Summary of TBA that will be entered on the IRIS database. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information to evaluate potential public health risks associated with environmental contaminants. The IRIS database is relied on for the development of risk assessments, site-specific environmental decisions, and rule making.
Description:
In August 2013, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for tert-Butyl Alcohol (tBA) to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in comments on the following:
- Draft literature search strategies
- The approach for identifying studies
- The screening process for selecting pertinent studies
- The resulting list of pertinent studies
- Preliminary evidence tables
- The process for selecting studies to include in evidence tables
- The quality of the studies in the evidence tables
URLs/Downloads:
Draft literature search and associated strategy and evidence tables for tert-Butyl Alcohol (tBA) (PDF, 61 pp, 856 KB, about PDF)All references sorted by author (tBA) (dynamic literature link - generated by HERO, leaving the IRIS website)
Literature selection process for tBA - (generated by HERO, leaving the IRIS website)
FR Notice: Aug 9, 2013
IRIS Public Science Meeting (Dec 2013)