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Uncertainty And Variability In Physiologically-Based Pharmacokinetic (PBPK) Models: Key Issues And Case Studies (Final Report)
Citation:
U.S. EPA. Uncertainty And Variability In Physiologically-Based Pharmacokinetic (PBPK) Models: Key Issues And Case Studies (Final Report). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-08/090.
Impact/Purpose:
This report summarizes some of the recent progress in characterizing uncertainty and variability in physiologically-based pharmacokinetic models and their predictions for use in risk assessment.
Description:
EPA announced the availability of the final report, Uncertainty and Variability in Physiologically-Based Pharmacokinetic (PBPK) Models: Key Issues and Case Studies. This report summarizes some of the recent progress in characterizing uncertainty and variability in physiologically-based pharmacokinetic models and their predictions for use in risk assessment.