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ToxCast: One Step in the NRC Vision of 21st Century Toxicology (S)
Citation:
KAVLOCK, R. J. ToxCast: One Step in the NRC Vision of 21st Century Toxicology (S). Presented at The International Council of Chemical Associations Long-Range Research Initiative (ICCA-LRI) Workshop , Amsterdam, NETHERLANDS, June 14 - 18, 2008.
Impact/Purpose:
ToxCast: One Step in the NRC Vision of 21st Century Toxicology (S)
Description:
The international community needs better predictive tools for assessing the hazards and risks of chemicals. It is technically feasible to collect bioactivity data on virtually all chemicals of potential concern ToxCast is providing a proof of concept for obtaining predictive, broad-based spectra of bioactivity. A critical need remains the elucidation of the majority of key biological processes involved in toxic responses Developmental toxicity represents one of the greatest challenges in this regard.