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EPAs ToxCast Research Program: Developing Predictive Bioactivity Signatures for Chemicals
Citation:
KAVLOCK, R. J. EPAs ToxCast Research Program: Developing Predictive Bioactivity Signatures for Chemicals. Presented at Health and Environmental Sciences Institute / Society of Toxicology Annual Meeting, Seattle, WA, March 14 - 20, 2008.
Impact/Purpose:
EPAs ToxCast Research Program is developing predictive bioactivity signatures for chemicals
Description:
The international community needs better predictive tools for assessing the hazards and risks of chemicals. It is technically feasible to collect bioactivity data on virtually all chemicals of potential concern ToxCast is providing a proof of concept for obtaining predictive, broad-based spectra of bioactivity. A critical need remains the elucidation of the majority of key biological processes involved in toxic responses Developmental toxicity represents one of the greatest challenges in this regard.