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Conazole Fungicides as Chiral Environmental Contaminants: Enantiomer Analysis and Enantioselectivity in Soil Slurries
Citation:
GARRISON, A. W., J. K. AVANTS, AND W. J. JONES. Conazole Fungicides as Chiral Environmental Contaminants: Enantiomer Analysis and Enantioselectivity in Soil Slurries . Presented at SETAC 29th Annual Meeting, Tampa, FL, November 16 - 20, 2008.
Impact/Purpose:
The main objective of this research is to determine the environmental occurrences, fate, and exposure of the enantiomers of selected chiral pesticides and other chiral organic pollutants. Chiral compounds, which exist as mixtures of enantiomers, include important environmental pollutants.
Description:
Conazoles are triazole compounds, many of which are in wide use as agricultural and medicinal fungicides. Opportunities exist for them to contaminate the environment and, since they are all chiral molecules, they are apt to be degraded enantioselectively by indigenous microbes. To characterize such enantioselectivity, it is necessary to analyze environmental samples for the separate conazole enantiomers. In most of the present study, enantiomer analysis was accomplished using a BGB-172 chiral GC column; detection was by GC-MS. For occasional confirmation, enantiomer analyses was performed by capillary electrophoresis (CE) in the micellar electrokinetic chromatography mode using various cyclodextrin chiral selectors. Research reported here involved the conazoles triadimefon, triadimenol, and propiconazole. Complete enantiomeric separation was achieved using either GC or CE for the enantiomers of all 3 fungicides.