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Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles
Citation:
Polshettiwar, V. AND R. S. VARMA. Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles. Chandrasekaran, Ganem, Guo-Qiang, Thomas, Wood, Yamamoto, Zard (ed.), TETRAHEDRON LETTERS. Elsevier Science Ltd, New York, NY, 49(5):879-883, (2008).
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Description:
A novel one-pot solvent free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles by condensation of acid hydrazide and triethyl orthoalkanates under microwave irradiations is reported. This green protocol was catalyzed efficiently by solid supported Nafion®NR50 and phosphorus pentasulfide in alumina (P4S10/Al2O3) with excellent yields.
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Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles
Record Details:
Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)
Product Published Date:01/28/2008
Record Last Revised:02/07/2008
OMB Category:Other
Record ID:
187650