Science Inventory

CatReg Software for Categorical Regression Analysis (Aug 2012)

Notice:

EPA is announcing an update to CatReg. The new CatReg version 2.3 is not only compatible with Microsoft Windows, but will also run in Mac OS X systems, with R-2.15.1 for Mac OS X installed. Functionality and plot display on both Windows and OS X platforms should be the same.. Version 2.3 of CatReg and a "readme" file describing the changes it includes can be downloaded from the "get the report" link below. In the upcoming months, EPA will also be releasing a new Windows-based beta version (version 3.0 beta) of CatReg. Check this website again in future months to obtain important CatReg information such as software updates and details regarding upcoming training opportunities.

Citation:

CatReg Software for Categorical Regression Analysis (Aug 2012). U.S. Environmental Protection Agency, Office of Research and Development, National Center For Environmental Assessment, Research Triangle Park Office, Research Triangle Park, NC, 2000.

Impact/Purpose:

The software was developed to support toxicity assessment for acute inhalation exposures, but the U.S. Environmental Protection Agency (EPA) encourages the broad application of this software.

Description:

CatReg is a computer program, written in the R (http://cran.r-project.org) programming language, to support the conduct of exposure-response analyses by toxicologists and health scientists. CatReg can be used to perform categorical regression analyses on toxicity data after effects have been assigned to ordinal severity categories (e.g., no effect, adverse effect, severe effect) and associated with up to two independent variables corresponding to the exposure conditions (e.g., concentration and duration) under which the effects occurred. CatReg calculates the probabilities of the different severity categories over the continuum of the variables describing exposure conditions. The categorization of observed responses allows expression of dichotomous, continuous, and descriptive data in terms of effect severity and supports the analysis of data from single studies or a combination of similar studies.

URLs/Downloads:

CatReg Training Slides   (PDF,114 pp, 752 KB,  about PDF)

CatReg Sample CSV Files

CatReg Software User Manual (R-version) (U.S. EPA, 2006)   (PDF,94 pp, 925 KB,  about PDF)

CatReg 2.3 R Files

Record Details:

Record Type: MODEL (REPORT)
Product Published Date: 09/21/2000
Record Last Revised: 02/17/2019
Record ID: 18162

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR ENVIRONMENTAL ASSESSMENT