EPA Science Inventory

MECHANISTIC COMPUTATIONAL MODEL OF OVARIAN STEROIDOGENESIS TO PREDICT BIOCHEMICAL RESPONSES TO ENDOCRINE ACTIVE COMPOUNDS.

Citation:

BREEN, M., D. L. VILLENEUVE, M. BREEN, G. T. ANKLEY, AND R. B. CONOLLY. MECHANISTIC COMPUTATIONAL MODEL OF OVARIAN STEROIDOGENESIS TO PREDICT BIOCHEMICAL RESPONSES TO ENDOCRINE ACTIVE COMPOUNDS. Dr. Gerald Saidel; Dr. Larry V. McIntire (ed.), Annals of Biomedical Engineering. Springer Netherlands, , Netherlands, 35(6):970-981, (2007).

Description:

Our study demonstrates the feasibility of using the steroidogenesis model to predict T and E2 concentrations, in vitro, while reducing model complexity with a steady-state assumption.

Purpose/Objective:

Our study demonstrates the feasibility of using the steroidogenesis model to predict T and E2 concentrations, in vitro, while reducing model complexity with a steady-state assumption.

URLs/Downloads:

MECHANISTIC COMPUTATIONAL MODEL OF OVARIAN STEROIDOGENESIS TO PREDICT BIOCHEMICAL RESPONSES TO ENDOCRINE ACTIVE COMPOUNDS.   Exit

Record Details:

Record Type: DOCUMENT (JOURNAL/PEER REVIEWED JOURNAL)
Start Date: 06/01/2007
Completion Date: 06/01/2007
Record Last Revised: 12/03/2008
Record Created: 05/16/2007
Record Released: 05/16/2007
OMB Category: Other
Record ID: 171103

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR COMPUTATIONAL TOXICOLOGY

IMMEDIATE OFFICE