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MANUAL FOR THE MICROSCOPIC DIAGNOSIS OF PROLIFERATIVE LIVER AND SKIN LESIONS IN THE BROWN BULLHEAD (AMEIURUS NEBULOSUS)
Citation:
BLAZER, V. S., J. W. FOURNIE, J. C. WOLF, AND M. J. WOLFE. MANUAL FOR THE MICROSCOPIC DIAGNOSIS OF PROLIFERATIVE LIVER AND SKIN LESIONS IN THE BROWN BULLHEAD (AMEIURUS NEBULOSUS). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-12/036, 2007.
Impact/Purpose:
This manual is the product of the Histopathology Subcommittee and the purpose is to describe neoplastic and non-neoplastic proliferative lesions of the liver and skin of the brown bullhead and suggest terminology that can be consistently used at AOCs throughout the Great Lakes and other areas.
Description:
The Great Lakes Water Quality Agreement, in which the US and Canada agreed to restore and preserve the biolgoical, physical and chemical integrity of the Great Lakes Basin Ecosystem, was first signed in 1972. In 1987, a Protocol was signed by both governments which defined Great Lakes Areas of Concern (AOC) as "geographic areas that fail to meet the general or specific objectives of the agreement where such failure has caused or is likely to cause impairment or beneficial use of the area's ability to support aquatic life." The U.S. and Canadian governments identified 43 such areas; 26 in the U.S., 12 in Canada and five shared between the U.S. and Canada on connecting river systems. The Great Lakes Water Quality Agreement, as amended via the 1987 protocol, directs the two federal governments to cooperate with state and provincial governments to develop and implement Remedial Action Plans (RAPs) for each AOC. The Protocol also called for reports on restorative progress and for the International Joint Commission (IJC) to review RPs proposed by the 43 Areas of Concern (IJC, 1987). Three ACO (Collingwood Harbor, Severn Sound and Oswego River) have been delisted and Presque Isle Bay has been designed an Area of Recovery.