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EXTRAHEPATIC METABOLISM IN CYP2E1 IN PBPK MODELING OF LIPOPHILIC VOLATILE ORGANIC CHEMICALS: IMPACTS ON METABOLIC PARAMETER ESTIMATION AND PREDICTION OF DOSE METRICS.
Citation:
YOON, M., M. C. MADDEN, AND H. A. BARTON. EXTRAHEPATIC METABOLISM IN CYP2E1 IN PBPK MODELING OF LIPOPHILIC VOLATILE ORGANIC CHEMICALS: IMPACTS ON METABOLIC PARAMETER ESTIMATION AND PREDICTION OF DOSE METRICS. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH. Taylor & Francis, Inc., Philadelphia, PA, 7(18):1527-1541, (2007).
Impact/Purpose:
Physiologically based pharmacokinetic (PBPK) models increasingly are available for environmental chemicals and applied in risk assessments.
Description:
Physiologically based pharmacokinetic (PBPK) models increasingly are available for environmental chemicals and applied in risk assessments.
Record Details:
Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)
Product Published Date:09/01/2007
Record Last Revised:12/03/2008
OMB Category:Other
Record ID:
162549