EPA Science Inventory

COMPUTATIONAL MODELING OF STEROIDOGENESIS TO PREDICT MOLECULAR RESPONSES TO ENDOCRINE DISRUPTORS

Citation:

BREEN, M., D. L. VILLENEUVE, K. H. Watanabe, G. T. ANKLEY, AND R. CONOLLY. COMPUTATIONAL MODELING OF STEROIDOGENESIS TO PREDICT MOLECULAR RESPONSES TO ENDOCRINE DISRUPTORS. Presented at (SETAC-Europe) Presentation for Society of Environmental Toxicology & Chemistry, Porto, PORTUGAL, May 20 - 24, 2007.

Description:

The deterministic model describes the biosynthetic pathways for the conversion of cholesterol to the steroid sex hormones and the gamete maturation inducing hormones secreted by the gonads in fish.

Purpose/Objective:

The deterministic model describes the biosynthetic pathways for the conversion of cholesterol to the steroid sex hormones and the gamete maturation inducing hormones secreted by the gonads in fish.

URLs/Downloads:

Computational Modeling of Steroidogenesis to predict Molecular Responses to Endocrine Disruptors   (PDF,NA pp, 11 KB,  about PDF)

Record Details:

Record Type: DOCUMENT (PRESENTATION/ABSTRACT)
Start Date: 05/21/2007
Completion Date: 05/21/2007
Record Last Revised: 12/03/2008
Record Created: 12/12/2006
Record Released: 12/12/2006
OMB Category: Other
Record ID: 161738

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR COMPUTATIONAL TOXICOLOGY

IMMEDIATE OFFICE