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ISSUES IN THE MEASUREMENT AND ASSESSMENT OF ENVIRONMENTAL EXPOSURES FOR A LARGE PROSPECTIVE COHORT STUDY
QUACKENBOSS, J. J., W. GALKE, S. VIET, AND D. MARKER. ISSUES IN THE MEASUREMENT AND ASSESSMENT OF ENVIRONMENTAL EXPOSURES FOR A LARGE PROSPECTIVE COHORT STUDY. Presented at 2007 Joint Statistical Meetings, Salt Lake City, UT, July 29 - August 02, 2007.
The overall goal of this research program is to identify those chemicals, pathways, and activities that represent the highest potential exposures to children and to determine the factors that influence these exposures. The following objectives will address this goal:
Revise and refine the existing research plan for children's exposure measurements research.
Collect measurement data on children's exposures.
Provide analytical support to children's pesticide exposure research.
Develop analytical methods for pesticides in duplicate diet food samples.
Develop and apply analytical methods for other chemicals including but not limited to brominated diphenyl ethers, phthalates, perfluorinated chemicals.
Evaluate the impact of chiral chemistry on the risk to children and exposure assessment.
Provide support to the National Children's Study.
Perform data analyses to fill critical data gaps.
Conduct analyses of dietary samples and refine the dietary model for the dietary exposure algorithm.
The National Children's Study (NCS) is a large-scale, multi-agency effort (lead by NIH, EPA, and CDC) to evaluate relationships among multiple exposures and changes in susceptibility over life stages, and subsequent health and developmental outcomes. In an invited presentation to the American Statistical Society's Joint Statistical Meetings, both statistical and logistical considerations for exposure assessment designs and approaches in the NCS will be discussed.