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A Compilation of In Vitro Rate and Affinity Values for Xenobiotic Biotransformation in Fish, Measured Under Physiological Conditions
Citation:
FITZSIMMONS, P. N., G. J. LIEN, AND J. W. NICHOLS. A Compilation of In Vitro Rate and Affinity Values for Xenobiotic Biotransformation in Fish, Measured Under Physiological Conditions. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. Elsevier Science Ltd, New York, NY, Part C 145:485-506, (2007).
Impact/Purpose:
To summarize in vitro rate and affinity data for xenobiotic biotransformation enzymes in fish.
Description:
This manuscript presents a summary of in vitro rate and affinity data for xenobiotic biotransformation enzymes in fish...One potential use of this data summary is to support in vitro to in vivo metabolism extrapolations which can be used as inputs to chemical kinetic models for fish to predict the impact of biotransformation on chemical bioaccumulation.
Record Details:
Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)
Product Published Date:05/15/2007
Record Last Revised:10/30/2008
OMB Category:Other
Record ID:
158224