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WITHIN AND BETWEEN-PERSON VARIATION IN ENVIRONMENTAL CONCENTRATIONS OF METALS, PAHS AND PESTICIDES MEASURED IN NHEXAS -MD
Citation:
EGEGHY, P. P. AND J. J. QUACKENBOSS. WITHIN AND BETWEEN-PERSON VARIATION IN ENVIRONMENTAL CONCENTRATIONS OF METALS, PAHS AND PESTICIDES MEASURED IN NHEXAS -MD. Presented at ISEA/ISEE 2006 , Paris, FRANCE, September 02 - 06, 2006.
Impact/Purpose:
The objectives for this task are to
Compile results and important findings from NERL-sponsored children's exposure studies;
Determine which pathways produce the greatest contribution to aggregate exposure among children for specific classes of pesticides;
Identify and quantify the factors that influence pesticide exposures among children;
Develop input parameters (e.g. multimedia pesticide distributions, exposure factor data) for exposure and dose models for assessing aggregate exposures and cumulative risks;
Evaluate exposure and dose models, including algorithms for estimating route-specific exposures, against real world data; and
Identify additional data gaps for modeling aggregate exposure and dose.
Description:
Results suggest that where information on variance components for a specific chemical in a specific media is not available, a chemical's compound class may provide guidance in selecting sample size and in apportioning resources between numbers of subjects and numbers of repeated measurements.