EPA Science Inventory

MATHEMATICAL MODEL OF STERIODOGENESIS TO PREDICT DYNAMIC RESPONSE TO ENDOCRINE DISRUPTORS

Citation:

BREEN, M., D. VILLENEUVE, G. T. ANKLEY, AND R. CONOLLY. MATHEMATICAL MODEL OF STERIODOGENESIS TO PREDICT DYNAMIC RESPONSE TO ENDOCRINE DISRUPTORS. Presented at BOARD OF SCIENTIFIC COUNSELORS (BOSC), RTP, NC, June 19 - 20, 2006.

Description:

WE ARE DEVELOPING A MECHANISTIC MATHEMATICAL MODEL OF THE INTRATESTICULAR AND INTRAOVARIAN METABOLIC NETWORK THAT MEDIATES STEROID SYNTHESIS, AND THE KINETICS FOR ENZYME INHIBITION BY EDCs TO PREDICT THE TIME AND DOSE-RESPONSE.

Purpose/Objective:

WE ARE DEVELOPING A MECHANISTIC MATHEMATICAL MODEL OF THE INTRATESTICULAR AND INTRAOVARIAN METABOLIC NETWORK THAT MEDIATES STEROID SYNTHESIS, AND THE KINETICS FOR ENZYME INHIBITION BY EDCs TO PREDICT THE TIME AND DOSE-RESPONSE.

URLs/Downloads:

Mathematical Model of Steriodogenesis to Predict Dynamic Response to Endocrine Disruptors   (PDF,NA pp, 9 KB,  about PDF)

Record Details:

Record Type: DOCUMENT (PRESENTATION/POSTER)
Start Date: 06/19/2006
Completion Date: 06/19/2006
Record Last Revised: 12/02/2008
Record Created: 07/19/2006
Record Released: 07/19/2006
OMB Category: Other
Record ID: 156271

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR COMPUTATIONAL TOXICOLOGY

IMMEDIATE OFFICE