EPA Science Inventory

ENANTIOMER-SPECIFIC FATE AND EFFECTS OF MODERN CHIRAL PESTICIDES

Citation:

GARRISON, A. W. ENANTIOMER-SPECIFIC FATE AND EFFECTS OF MODERN CHIRAL PESTICIDES. Presented at Workshop on Chiral Xeniobiotics, Birmingham, UK, March 28, 2006.

Description:

This slide presentation presents enantiomer-specific fate and effects of modern chiral pesticides. The research areas presented were analytical separation of enantiomers; environmental occurrence of enantiomers; transformation rates and enantioselectivity; bioaccumulation; and enantioselectivity effects. Conclusions of the presentation were many modern pesticides are chiral; capillary electrophoresis is useful for laboratory studies of pesticide transformation; microbial transformation is usually observed to be enantioselective, but it is not possible at this time to predict the direction or extent of selectivity in a different environment; and enantiomers usually differ in their effects, including toxicity and ED activity, but little definitive work has been done with pesticides; metabonomics, proteomics and other modern molecular biochemistry techniques are applicable to investigate toxicity mechanisms; accurate risk assessment requires investigation of the fate and effects of each enantiomer of a chiral pesticide; and the ultimate goal of this research is to show whether the manufacture and use of single-enantiomer pesticides is of benefit to the environment.

Purpose/Objective:

To determine the environmental occurrences, fate, and effects of the enantiomers of selected chiral pesticides and other chiral pollutants.

URLs/Downloads:

Record Details:

Record Type: DOCUMENT (PRESENTATION/ABSTRACT)
Start Date: 03/28/2006
Completion Date: 03/28/2006
Record Last Revised: 06/21/2006
Record Created: 04/20/2006
Record Released: 04/20/2006
Record ID: 151983

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL EXPOSURE RESEARCH LAB

ECOSYSTEMS RESEARCH DIVISION

PROCESSES & MODELING BRANCH