Citation:

Reddy, T., G. Olson, F. Daniel, AND M. Robinson. CARCINOGENIC EVALUATION OF 2,3-DIMETHYL-2,3-DINITROBUTANE VIA THE MOUSE SKIN BIOASSAY. Journal of Applied Toxicology 14(3):231-232, (1994).

Description:

Female SENCAR mice initiated with 2,3-dimethyl-2,3dimethyl-2,3-dinitrobutane (DMDNB) and promoted with 12-0-tetradecanoylphorol-13-acetate (TPA) via the SENCAR mouse skin bioassy did not exhibit a significant increase in skin tumors. The mice received 20 mg kg-1 DMDNE divided into six intragastric doses over 2 weeks and were promoted three times per week for 20 weeks.

Record Details:

Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)

Product Published Date:01/01/1994

Record Last Revised:12/22/2005

Record ID: 14463