Science Inventory

An Evaluation of the Human Carcinogenic Potential of Ethylene Glycol Butyl Ether (EGBE)

Citation:

U.S. EPA. An Evaluation of the Human Carcinogenic Potential of Ethylene Glycol Butyl Ether (EGBE). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-04/123, 2005.

Impact/Purpose:

An NTP (1998; 2000) study has reported some evidence of carcinogenic activity in male B6C3F1 mice based on increased incidence of hemangiosarcomas of the liver, and some evidence of carcinogenic activity in female B6C3F1 mice based on increased incidence of forestomach squamous cell papillomas or carcinomas.

Description:

This position paper, An Evaluation of the Human Carcinogenic Potential of Ethylene Glycol Butyl Ether, was developed in support of the EPA's evaluation of a petition from the American Chemistry Council requesting to delist EGBE per the Clean Air Act Amendments (CAAA), Title III, section 112(b)(1). The position paper was a key component of the Agency's recent determination to grant this petition. It will also be used in the Agency's IRIS assessment of ethylene glycol butyl ether (EGBE).

Record Details:

Record Type:DOCUMENT( PUBLISHED REPORT/ REPORT)
Product Published Date:07/08/2005
Record Last Revised:02/02/2017
Record ID: 135268