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INTEGRATION OF BIOMONITORING EXPOSURE DATA INTO THE RISK ASSESSMENT PROCESS
Citation:
SHELDON, L. S., H. ZENICK, N. DOERRER, L. NEEDHAM, S. ROBINSON, AND E. FAUSTMAN. INTEGRATION OF BIOMONITORING EXPOSURE DATA INTO THE RISK ASSESSMENT PROCESS. Presented at EPA Science Forum 2005, Washington, DC, May 16 - 18, 2005.
Impact/Purpose:
The objective of this task is to conduct cooperative research to implement a source-to-dose human exposure modeling framework to increase understanding of the exposure-to-dose system and to improve the risk assessment process. Research will address application of the modeling framework to address specific agency problems, evaluation of the modeling framework, and further development work that may be required based on application and evaluation of the human exposure source-to-dose modeling framework and tools.
Description:
Improved biomonitoring techniques are being used to measure very low levels of environmental chemicals in the tissues of adults and children. Public and private demand for biomonitoring data are on the increase worldwide. In the United States alone, government-sponsored programs include the National Health and Nutrition Examination Survey (NHANES) conducted by the CDC, the CDC National Environmental Public Health Tracking Program, the Interagency National Children's Study, the Interagency Agricultural Health Study, the Farm Family Exposure Study, the pilot studies conducted by the U.S. Environmental Protection Agency (U.S. EPA) as part of the National Human Exposure Assessment Survey (NHEXAS), and the new project on Human Biomonitoring for Environmental Toxicants undertaken by the National Academy of Sciences.