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Proposed Guidelines for Efficacy Testing of Topically Applied Pesticides Used Against Certain Ectoparasitic Pests on Pets
Citation:
Proposed Guidelines for Efficacy Testing of Topically Applied Pesticides Used Against Certain Ectoparasitic Pests on Pets.
Impact/Purpose:
The Agency is seeking advice and recommendations from the SAP on scientific issues associated with the proposed revised EPA guideline. The Agency believes the current draft guideline represents the state of the science with regard to efficacy testing for these products. EPA is committed to reducing the use of animals in testing (https://www.regulations.gov/document?D=EPA-HQ-OPP-2016-0093-0003). However, at this time no reliable non-animal alternatives are available to avoid the use of animals for efficacy testing of fleas, ticks, mosquitoes and biting flies. As part of the SAP, EPA is soliciting comment from the panel on approaches that may, in the future, support the replacement or reduction of animal use in efficacy testing of ectoparasitic pests on pets.
Description:
The proposed guideline applies to products in any topically applied formulation, such as a spray, spot-on, collar, shampoo, or dust, if intended to be directly applied to pets for a pesticidal purpose such as to kill, repel, or control ticks, fleas, mosquitoes, and biting flies. This guideline does not apply to those products exempt from FIFRA Registration under 40 CFR 152.25, products applied to humans or livestock, or product performance testing described in other Agency guidelines. In addition to guidance for testing efficacy against fleas, ticks, mosquitoes, and biting flies, the proposed guideline also includes testing methods for evaluating efficacy under simulated environmental conditions.
URLs/Downloads:
SAP Review of Proposed Guidelines for Efficacy Testing of Topically Applied Pesticides Used Against Certain Ectoparasitic Pests on Pets (June 11-14, 2019), EPA Response (PDF, 98 pp, 1439 KB, about PDF)Meeting Information for the June 11-14, 2019 SAP
Draft Product Performance Test Guidelines; OCSPP 810.3300: Treatments Topically Applied to Pets to Control Certain Invertebrate Ectoparasitic Pests (PDF, NA pp, 357 KB, about PDF)
Transmission of Background Materials and Charge (PDF, NA pp, 431 KB, about PDF)
Peer Review Plan (PDF, NA pp, 42 KB, about PDF)
Meeting Minutes and Final Report No. 2019-02 (PDF, NA pp, 3359 KB, about PDF)
Sample Size for Pet Product Studies (PDF, NA pp, 1043 KB, about PDF)
Charge to the Panel (PDF, NA pp, 134 KB, about PDF)
Product Performance Test Guidelines OCSPP 810.3300: The Efficacy of Topically Applied Pet Products Against Certain Invertebrate Pests (PDF, 23 pp, 384 KB, about PDF)