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Exposure and Hazard Information for Five PBT Chemicals
Citation:
Exposure and Hazard Information for Five PBT Chemicals.
Impact/Purpose:
Section 6(h) of the Toxics Substances Control Act (TSCA) directs EPA to issue regulations under 6(a) for certain Persistent Bioaccumulative and Toxic (PBT) chemical substances that were identified in EPA’s TSCA Work Plan for Chemical Assessments: 2014 update. The chemicals that were ranked high or moderate for either persistence and bioaccumulation, are present on the TSCA 2014 workplan chemical list that are not metals, that do not have problem formulation completed, do not have a review under section 5, and do not have a consent agreement under section 4 are the following five chemicals: Decabromodiphenyl ethers (DECA); Hexachlorobutadiene (HCBD); Pentachlorothiophenol (PCTP); Phenol, isopropylated, phosphate (3:1) (PIP3/ ITPP); and 2,4,6-Tris(tert-butyl) phenol (2, 4, 6 TRIS). No risk evaluation is required for these PBT chemicals. EPA has drafted an exposure and Use Assessment and a Human Health and Environmental Hazard Summary, in response to the TSCA section 6(h) requirements to summarize conclusions of toxicity and whether there is likely exposure to these PBT chemicals. These documents contain the following components: • Chemistry, physical-chemical properties and expected transport and partitioning. • Characterization of manufacture (including import), processing, uses and potential sources of exposure. • Summary of available monitoring data, concentrations and doses. • Characterization of trends in releases/exposures over time. • Summary of environmental hazard (written and tabular summaries). • Summary of human health hazard (written and tabular summaries). • Strategy for identifying environmental hazard summary information. • Strategy for identifying human health summary information. • Supplemental Files that identify how environmental information was searched, screened, and evaluated.
Description:
The Agency has organized letter peer reviews of EPA’s 1) Exposure and Use Assessment and 2) Human Health and Environmental Hazard Summary for the five persistent, bioaccumulative, and toxic (PBT) chemicals selected for expedited review under the amended Toxic Substances Control Act (TSCA).
URLs/Downloads:
Environmental and Human Health Hazard Summary for Five PBT Chemicals (PDF, NA pp, 1039 KB, about PDF)Transmittal of Peer Reviewer Responses (PDF, NA pp, 182 KB, about PDF)
Peer Reviewer Responses to Charge Questions for Five PBT Chemicals (PDF, NA pp, 3846 KB, about PDF)
Exposure and Use Assessment Peer Review Charge Questions (PDF, NA pp, 367 KB, about PDF)
Environmental and Human Health Hazard Summary Peer Review Charge Questions (PDF, NA pp, 369 KB, about PDF)
Letter Peer Reviews, Exposure and Hazard Information, 5 PBTs
Transmittal Memorandum (PDF, NA pp, 260 KB, about PDF)
Supplemental Information for Exposure and Use Assessment PBTs (PDF, NA pp, 3779 KB, about PDF)
Exposure and Use Assessment for Five PBT Chemicals (PDF, NA pp, 7962 KB, about PDF)