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AUTOMATED ANALYSIS OF AQUEOUS SAMPLES CONTAINING PESTICIDES, ACIDIC/BASIC/NEUTRAL SEMIVOLATILES AND VOLATILE ORGANIC COMPOUNDS BY SOLID PHASE EXTRACTION COUPLED IN-LINE TO LARGE VOLUME INJECTION GC/MS
FORD, R., D. A. KOVACS, D. GREGG, AND D. SISCANAW. AUTOMATED ANALYSIS OF AQUEOUS SAMPLES CONTAINING PESTICIDES, ACIDIC/BASIC/NEUTRAL SEMIVOLATILES AND VOLATILE ORGANIC COMPOUNDS BY SOLID PHASE EXTRACTION COUPLED IN-LINE TO LARGE VOLUME INJECTION GC/MS. Presented at PittCon 2007 Conference, chicago, IL, February 25, 2007 - March 02, 3007.
To inform the public.
Data is presented on the development of a new automated system combining solid phase extraction (SPE) with GC/MS spectrometry for the single-run analysis of water samples containing a broad range of organic compounds. The system uses commercially available automated in-line 10-mL sample extraction with large volume injection and GC/MS. Two commercially available SPE sorbents used in series allow extraction of both polar and non-polar compounds. In-line injection of the 90-uL extract from a 10-mL sample resulted in detection limits 10-100 times lower than recommended EPA Method 8270 limits for semi-volatiles. Variance in SPE extraction efficiency is directly monitored and quantitative accuracy improved through the use of “internal” deuterated and non-deuterated standards/surrogates added to calibration standards, blanks and samples prior to automated SPE concentration. System performance has been demonstrated for 92 target organic compounds, including acidic, basic and neutral semi-volatile compounds as well as chlorinated- and nitrogen-containing pesticides. This detection system has also been successfully applied to the analysis of a range of Method 8270 semi-volatile compounds in complex matrices derived from water-isopropanol extracts of contaminated sediments, resulting in enhanced sample throughput with optimum detection limits. Preliminary work has also demonstrated the potential for quantitation of both volatile and semi-volatile compounds in a single analysis. The performance and flexibility of this system along with increases in automation and reduction in solvent usage and accompanying analyst exposure make this an attractive alternative for the analysis of volatile and semi-volatile organic compounds in aqueous samples.
Record Details:Record Type: DOCUMENT (PRESENTATION/ABSTRACT)
Organization:U.S. ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF RESEARCH AND DEVELOPMENT
NATIONAL RISK MANAGEMENT RESEARCH LABORATORY
GROUND WATER AND ECOSYSTEMS RESTORATION DIVISION
SUBSURFACE REMEDIATION BRANCH