Science Inventory

SOLVENT-FREE TETRAHYDROPYRANYLATION (THP) OF ALCOHOLS AND PHENOLS AND THEIR REGENERATION BY CATALYTIC ALUMINUM CHLORIDE HEXAHYDRATE

Citation:

Namboodiri**, V AND R S. Varma*. SOLVENT-FREE TETRAHYDROPYRANYLATION (THP) OF ALCOHOLS AND PHENOLS AND THEIR REGENERATION BY CATALYTIC ALUMINUM CHLORIDE HEXAHYDRATE. doi:10.1016/S0040-40, S. Chandrasekaran, B. Ganem, Lin Guo-Qiang, E.J. Thomas, J. Wood, Y. Yamamoto, S.Z. Zard (ed.), TETRAHEDRON LETTERS. Elsevier Science Ltd, London, Uk, 43(7):1143-1146, (2002).

Impact/Purpose:

publish information

Description:

Catalytic amount of aluminum chloride hexahydrate enables solvent-free tetrahydropyranylation (THP) of alcohols and phenols at moderate temperatures. A simple addition of methanol helps to regenerate the corresponding alcohols and phenols thus rendering these protection and deprotection sequences as very efficient transformation at high substrate to catalyst ratio.

URLs/Downloads:

SOLVENT-FREE TETRAHYDROPYRANYLATION (THP) OF ALCOHOLS AND PHENOLS AND THEIR REGENERATION BY CATALYTIC ALUMINUM CHLORIDE HEXAHYDRATE   Exit

Record Details:

Record Type: DOCUMENT (JOURNAL/PEER REVIEWED JOURNAL)
Product Published Date: 02/11/2002
Record Last Revised: 07/16/2008
OMB Category: Other
Record ID: 115281

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL RISK MANAGEMENT RESEARCH LABORATORY

SUSTAINABLE TECHNOLOGY DIVISION

CLEAN PROCESSES BRANCH