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A PHYSIOLOGICALLY BASED TOXICOKINETIC MODEL FOR DIETARY UPTAKE OF HYDROPHOBIC ORGANIC COMPOUNDS IN FISH: II. SIMULATION OF CHRONIC EXPOSURE SCENARIOS
Citation:
Nichols, J. W., P N. Fitzsimmons, AND F W. Whiteman. A PHYSIOLOGICALLY BASED TOXICOKINETIC MODEL FOR DIETARY UPTAKE OF HYDROPHOBIC ORGANIC COMPOUNDS IN FISH: II. SIMULATION OF CHRONIC EXPOSURE SCENARIOS. TOXICOLOGICAL SCIENCES 77(2):219-229, (2004).
Description:
A physiologically based toxicokinetic (PBTK) model for dietary uptake of hydrophobic organic compounds in fish was used to simulate dosing scenarios commonly encountered in experimental and field studies. . . . Relatively low rates of metabolism or growth were shown to have a substantial impact on steady-state biomagnification of chemical residues...
Record Details:
Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)
Product Published Date:02/25/2004
Record Last Revised:12/22/2005
Record ID:
76584