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ENDOCRINE-DISRUPTING CHEMICALS IN THE ENVIRONMENT: ASSESSING POTENTIAL EFFECTS IN WILDLIFE
Ankley, G T. ENDOCRINE-DISRUPTING CHEMICALS IN THE ENVIRONMENT: ASSESSING POTENTIAL EFFECTS IN WILDLIFE. Presented at 22nd Midwest Environmental Chemistry Workshop, Michigan Technical University, Houghton, MI, October 1-3, 1999.
Recent evidence suggests that xenobiotic chemicals which mimic/block the action of key hormones in a variety of endocrine pathways may be responsible for adverse effects both in humans and wildlife. This talk will provide an overview of instances in which endocrine-disrupting chemicals (EDCs) have been associated with, or hypothesized to be responsible for, impacts in wildlife; examples will include (a) early-life stage mortality in Great Lakes fish and avian species, (b) malformations in North American frogs, (c) reproductive/developmental anamalies in alligators from Central Florida, (d) hermaprodism in fish from the UK, and (e) abnormal reproductive development (imposex) in marine gastropods from around the world. Also presented will be an overview of the activities of the US Environmental Protection Agency with respect to screening for potential EDCs, and conducting research to better characterize their effects in the environment.