Science Inventory

IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) (Preliminary Assessment Materials)


EPA hosted an IRIS public science meeting on December 12-13, 2013, to provide an opportunity for the public to give input and participate in an open discussion regarding preliminary materials that were prepared for the IRIS chemical, ethyl tert-butyl ether (ETBE), prior to the development of the draft assessment.


U.S. EPA. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) (Preliminary Assessment Materials). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-13/108, 2013.


The draft Toxicological Review of Ethyl Tertiary Butyl Ether provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to ethyl tertiary butyl ether.


In August 2013, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for ETBE to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in comments on the following:

  • Draft literature search strategies
    • The approach for identifying studies
    • The screening process for selecting pertinent studies
    • The resulting list of pertinent studies
  • Preliminary evidence tables
    • The process for selecting studies to include in evidence tables
    • The quality of the studies in the evidence tables
The literature search strategy, which describes the processes for identifying scientific literature, contains the studies that EPA considered and selected to include in the evidence tables. The preliminary evidence tables and exposure-response arrays present the key study data in a standardized format. The evidence tables summarize the available critical scientific literature. The exposure-response figures provide a graphical representation of the responses at different levels of exposure for each study in the evidence table.


FR Notice: Aug 9, 2013   Exit

Literature selection process for ETBE - (generated by HERO, leaving the IRIS website)

IRIS December Bimonthly Meeting -- ETBE Presentations

All references sorted by author (ETBE) (dynamic literature link - generated by HERO, leaving the IRIS website)

Draft literature search and associated strategy and evidence tables for ETBE   (PDF,58 pp, 1472 KB,  about PDF)

Record Details:

Product Published Date: 02/24/2014
Record Last Revised: 12/13/2017
OMB Category: Other
Record ID: 253754