Science Inventory

IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) (Interagency Science Consultation Draft)

Citation:

U.S. EPA. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) (Interagency Science Consultation Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-14/373, 2014.

Impact/Purpose:

EPA is undertaking an new health assessment for ethyl tertiary butyl ether (ETBE) for the Integrated Risk Information System (IRIS). The outcome of this project will be a Toxicological Review and IRIS Summary of ETBE that will be entered on the IRIS database. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information in support of two steps of the risk assessment process, i.e., hazard identification and dose-response evaluation. IRIS assessments are used nationally and internationally in combination with specific situational exposure assessment information to evaluate potential public health risks associated with environmental contaminants. The IRIS database is relied on for the development of risk assessments, site-specific environmental decisions, and rule making.

Description:

In September 2016, EPA released the draft IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) for public comment and discussion. The draft assessment was reviewed internally by EPA and by other federal agencies and White House Offices before public release. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science consultation materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Ethyl Tertiary Butyl Ether are posted on this site.

URLs/Downloads:

IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (Interagency Science Consultation Review Draft)   (PDF,233 pp, 3637 KB,  about PDF)

2. OMB / OSTP Comments on ETBE   (PDF,4 pp, 141 KB,  about PDF)

Draft peer review charge for reviewers (Interagency Science Consulation Draft)   (PDF,3 pp, 159 KB,  about PDF)

IRIS Toxicological Review of Ethyl Tertiary Butyl Ether -- Supplemental Information (Interagency Science Consultation Draft)   (PDF,124 pp, 1874 KB,  about PDF)

EPA's Response to Major Science Comments (Interagency Science Consultation Draft)   (PDF,2 pp, 105 KB,  about PDF)

1. NTP Comments on ETBE   (PDF,3 pp, 193 KB,  about PDF)

Record Details:

Record Type: DOCUMENT (IRIS ASSESSMENT)
Product Published Date: 06/16/2016
Record Last Revised: 12/13/2017
OMB Category: Influential
Record ID: 81311

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR ENVIRONMENTAL ASSESSMENT

IMMEDIATE OFFICE

INTEGRATED RISK INFORMATION STAFF