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PBPK model and evaluation examples: Chromium & Chloroform-presentation
Citation:
Sasso, A. PBPK model and evaluation examples: Chromium & Chloroform-presentation. OEHHA PBPK Workshop, na, September 30, 2019.
Impact/Purpose:
This is a presentation to California EPA as part of an in-person training seminar. It outlines physiologically-based pharmacokinetic (PBPK) model application and development issues, and presents two examples (hexavalent chromium and chloroform).
Description:
Physiologically-based pharmacokinetic (PBPK) models can estimate absorption, distribution, metabolism, and elimination (ADME) of chemicals in the body. There are multiple alternative models or analyses in the literature, and the models may be of low quality or unsuitable for some uses.
Record Details:
Record Type:DOCUMENT( PRESENTATION/ SLIDE)
Product Published Date:09/30/2019
Record Last Revised:07/15/2021
OMB Category:Other
Record ID:
352285