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Human Health Toxicity Values for Perfluorobutane Sulfonic Acid and Related Compound Potassium Perfluorobutane Sulfonate
In April 2021, EPA announced the release of the final report Human Health Toxicity Values for Perfluorobutane Sulfonic Acid (CASRN 375-73-5) and Related Compound Potassium Perfluorobutane Sulfonate (CASRN 29420-49-3).
Citation:
U.S. EPA. Human Health Toxicity Values for Perfluorobutane Sulfonic Acid and Related Compound Potassium Perfluorobutane Sulfonate. U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-20/345F, 2021.
Impact/Purpose:
The PFBS human health toxicity values presented in this assessment were developed based on the best available science. The assessment provides high-quality evaluations and conclusions drawn from publicly available information on the toxicity of PFBS. This assessment is not a regulation; rather, it provides a critical part of the scientific foundation for risk assessment decision making.
Description:
Perfluorobutane sulfonic acid (PFBS) is a member of a larger group of per- and polyfluoroalkyl substances (PFAS). This assessment is part of EPA’s efforts to increase the amount of research and information that is publicly available on chemicals in the PFAS family. It was developed by the U.S. EPA’s Office of Research and Development (ORD) Center for Public Health and Environmental Assessment (CPHEA).
The PFBS toxicity assessment is one of the key goals of the Agency’s PFAS Action Plan and provides qualitative and quantitative toxicity information that can be used by federal partners, states, tribes, and local communities, along with specific exposure and other relevant information to determine, under the appropriate regulations and statutes, if and when it is necessary to take action to address potential risk associated with human exposures to this PFAS. This assessment is available for use across multiple U.S. EPA program and regional offices, other federal agencies, states, tribes, external stakeholders, and other entities as needed. One use of this assessment is to update and replace the existing 2014 Provisional Peer-Reviewed Toxicity Value (PPRTV) assessment for PFBS used by the U.S. EPA’s Superfund Program.
URLs/Downloads:
Human Health Toxicity Values for Perfluorobutane Sulfonic Acid (CASRN 375-73-5) and Related Compound Potassium Perfluorobutane Sulfonate (CASRN 29420-49-3) (PDF, 169 pp, 6408 KB, about PDF)EPA Response to Peer Review Comments on the 2020 Draft Report (PDF, 91 pp, 710 KB, about PDF)
Fact Sheet: Toxicity Assessment for PFBS (PDF, 4 pp, 104 KB, about PDF)
Technical Fact Sheet: Toxicity Assessment for PFBS (PDF, 7 pp, 221 KB, about PDF)
Appendix D. HAWC User Guide and Frequently Asked Questions (PDF, 7 pp, 516 KB, about PDF)
Appendix D. HAWC User Guide and Frequently Asked Questions (PDF, 7 pp, 516 KB, about PDF)