Science Inventory

IRIS Assessment Plan for Ammonia and Ammonium Salts Noncancer Oral (Scoping and Problem Formulation Materials)

Notice:

EPA announced the availability of the IRIS Assessment Plan for Ammonia and Ammonium Salts: Noncancer Assessment for Oral Exposure (Scoping and Problem Formulation Materials) for a 30-day public comment period as announced in an April 16, 2018 Federal Register Notice.

Citation:

U.S. EPA. IRIS Assessment Plan for Ammonia and Ammonium Salts Noncancer Oral (Scoping and Problem Formulation Materials). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-18/041, 2018.

Impact/Purpose:

The IAP communicates to the public the plan for assessing each individual chemical and includes summary information on the IRIS Program’s scoping and initial problem formulation, objectives and specific aims for the assessment, and a PECO framework that outlines the evidence considered most pertinent to the assessment; and identification of key areas of scientific complexity.

Description:

In April 2018, EPA released the draft IRIS Assessment Plan for Ammonia and Ammonium Salts Noncancer Oral. An IRIS Assessment Plan (IAP) communicates to the public the plan for assessing each individual chemical and includes summary information on the IRIS Program’s scoping and initial problem formulation; objectives and specific aims for the assessment; the PECO (Populations, Exposures, Comparators, and Outcomes) criteria that outlines the evidence considered most pertinent to the assessment; and identification of key areas of scientific complexity. The PECO provides the framework for developing literature search strategies and inclusion/exclusion criteria, particularly with respect to evidence stream (i.e., human, animal, mechanistic), exposure measures and outcome measures.

URLs/Downloads:

Primary Literature Search References Sorted By Author (Ammonia - Noncancer Oral Exposure)

IRIS Assessment Plan for Ammonia and Ammonium Salts: Noncancer Assessment for Oral Exposure (Scoping and Problem Formulation Materials)   (PDF,32 pp, 807 KB,  about PDF)

Docket for EPA-HQ-ORD-2018-0132   Exit

FR Notice: Apr 16, 2018   Exit

Record Details:

Record Type: DOCUMENT (ASSESSMENT DOCUMENT)
Product Published Date: 04/16/2018
Record Last Revised: 05/24/2018
OMB Category: Other
Record ID: 340338

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR ENVIRONMENTAL ASSESSMENT

IMMEDIATE OFFICE

PROGRAM SUPPORT STAFF