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IRIS Toxicological Review of Trimethylbenzenes (External Review Draft)
EPA is announcing the release of the draft IRIS Toxicological Review of Trimethylbenzenes (External Review Draft) for a 60-day public review and comment period.
Citation:
U.S. EPA. IRIS Toxicological Review of Trimethylbenzenes (External Review Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-11/012Aa-Ab, 2012.
Impact/Purpose:
EPA is reassessing its IRIS toxicological review of Trimethylbenzenes (1,2,3-;1,2,4-;1,3,5-). This trimethylbenzene reassessment consists of an oral reference dose (RfD), an inhalation reference concentration (RfC), an inhalation unit risk (IUR) and a cancer weight of evidence descriptor. This is the first assessment developing an RfC or IUR for this compound. This assessment is intended to provide human health data to support agency regulatory decisions.
Description:
EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of trimethylbenzenes that will appear in the Integrated Risk Information System (IRIS) database.
URLs/Downloads:
IRIS Toxicological Review of Trimethylbenzenes (External Review Draft) (PDF, 138 pp, 1942 KB, about PDF)Supplemental Information for Trimethylbenzenes (External Review Draft) (PDF, 220 pp, 9710 KB, about PDF)
Draft Charge to External Peer Reviewers (PDF, 6 pp, 219 KB, about PDF)
FR Notice: Jun 29, 2012