Science Inventory

IRIS Toxicological Review of Hexabromocyclododecane (HBCD) (Preliminary Assessment Materials)


EPA hosted an IRIS public science meeting on April 23, 2014, to provide an opportunity for the public to give input and participate in an open discussion regarding preliminary materials that were prepared for the IRIS chemical, hexabromocyclododecane (HBCD), prior to the development of the draft assessment.


U.S. EPA. IRIS Toxicological Review of Hexabromocyclododecane (HBCD) (Preliminary Assessment Materials). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-13/235, 2014.




In March 2014, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for HBCD to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in comments on the following:

  • Draft literature search strategies
    • The approach for identifying studies
    • The screening process for selecting pertinent studies
    • The resulting list of pertinent studies
  • Preliminary evidence tables
    • The process for selecting studies to include in evidence tables
    • The quality of the studies in the evidence tables
The literature search strategy, which describes the processes for identifying scientific literature, contains the studies that EPA considered and selected to include in the evidence tables. The preliminary evidence tables and exposure-response arrays present the key study data in a standardized format. The evidence tables summarize the available critical scientific literature. The exposure-response figures provide a graphical representation of the responses at different levels of exposure for each study in the evidence table.


Literature selection process for the HBCD primary literature

Scoping information, preliminary literature search, associated strategy and evidence tables for HBCD   (PDF,84 pp, 1319 KB,  about PDF)

IRIS April 2014 Bimonthly Meeting -- HBCD Presentations

Primary literature search references sorted by author (HBCD)

Record Details:

Product Published Date: 06/27/2011
Record Last Revised: 12/11/2017
OMB Category: Influential
Record ID: 236365